Columns for physical separation of fractions are laboratory devices used to separate mixtures of different substances based on their physical properties. These columns are commonly used in chemistry, biochemistry, and other fields that require the separation of complex mixtures. The principle behind column separation is the differential partitioning of substances between two phases, one stationary and the other mobile, as they pass through a column packed with a suitable material. The stationary phase can be a solid or a liquid, while the mobile phase is typically a liquid or a gas. The most common type of column used for physical separation of fractions is the chromatography column. Chromatography is a technique that exploits the differential partitioning of substances between a stationary phase and a mobile phase. The stationary phase is typically a solid material packed into a column, while the mobile phase is a liquid or a gas that flows through the column. As the mixture passes through the column, the different components of the mixture interact differently with the stationary phase, leading to their separation based on their physical properties such as size, charge, or polarity. Other types of columns used for physical separation of fractions include distillation columns, which separate mixtures based on differences in boiling points, and extraction columns, which separate mixtures based on differences in solubility. Distillation columns are commonly used in the chemical industry to separate complex mixtures into their individual components, while extraction columns are used in the pharmaceutical industry to extract active compounds from natural sources. In conclusion, columns for physical separation of fractions are essential laboratory devices used to separate complex mixtures based on their physical properties. Chromatography columns are the most common type of column used for this purpose, but distillation and extraction columns are also used in specific applications. These columns have revolutionized the field of analytical chemistry and have enabled scientists to isolate and study individual components of complex mixtures.
chromatography, distillation, extraction, physical properties, laboratory
CITATION : "Paul Jackson. 'Columns For Physical Separation Of Fractions.' Design+Encyclopedia. https://design-encyclopedia.com/?E=266701 (Accessed on July 17, 2025)"
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